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![]() ![]() ![]() Vitamin D comes from two sources: skin synthesis from the precursor-7-dehydrocholesterol-to cholecalciferol upon UVB radiation, and from the diet as cholecalciferol (D 3) or ergocalciferol (D 2). According to most of the authors, more randomized controlled trials with effective, large populations are needed to explore the preventive effect of vitamin D supplementation on viral influenza infections. The most important point is to realise that the broad spectrum of this vitamin’s activity does not exclude such a possibility. The survey of the literature data generates some controversies and doubts about the possible role of vitamin D in the prevention of influenza virus. Edgar Hope-Simpson, it would be crucial to prove it from a potential easy and cheap prophylaxis or therapy support perspective as far as influenza infections are concerned. Because vitamin D could be acknowledged as a “seasonal stimulus”, as defined by R. A significant effect is also the suppression of inflammatory processes. The possible role of vitamin D in infections is implied from its impact on the innate and adaptive immune responses. Vitamin D generates many extraskeletal effects due to the vitamin D receptor (VDR) which is present in most tissues throughout the body. ![]()
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